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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BIRC3 All Species: 11.52
Human Site: S593 Identified Species: 23.03
UniProt: Q13489 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13489 NP_001156.1 604 68372 S593 R K C P I C R S T I K G T V R
Chimpanzee Pan troglodytes XP_508719 604 68367 S593 R K C P I C R S T I K G T V R
Rhesus Macaque Macaca mulatta XP_001095970 604 68451 S593 R K C P I C R S T I K G T V R
Dog Lupus familis XP_538165 615 69039 T604 D K C P M C Y T V I T F K Q K
Cat Felis silvestris
Mouse Mus musculus O08863 600 67180 G589 R K C P I C R G T I K G T V R
Rat Rattus norvegicus Q9R0I6 496 56054 V486 K C P M C C T V I T F K Q K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509526 607 68021 G596 R K C P I C R G T I K G T V R
Chicken Gallus gallus Q90660 611 68991 G600 R K C P I C R G T I K G T V R
Frog Xenopus laevis A5D8Q0 488 55110 I478 K C P I C C T I I E R R Q K I
Zebra Danio Brachydanio rerio NP_919376 628 70080 G617 R K C P I C R G M V K G T V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24307 498 54520 D488 N C P M C R A D I K G F V R T
Honey Bee Apis mellifera XP_396819 518 59795 E508 Y C L M C R Q E I K A I V R T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.6 20.6 N.A. 74 33.4 N.A. 73.4 67.4 32.7 54.2 N.A. 30.7 32.4 N.A. N.A.
Protein Similarity: 100 99.3 98 37.2 N.A. 85.4 48 N.A. 84.6 79.7 50.1 68.9 N.A. 48.6 51.8 N.A. N.A.
P-Site Identity: 100 100 100 33.3 N.A. 93.3 6.6 N.A. 93.3 93.3 6.6 80 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 100 100 53.3 N.A. 93.3 13.3 N.A. 93.3 93.3 20 86.6 N.A. 0 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % A
% Cys: 0 34 67 0 34 84 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 17 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 34 0 0 9 59 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 59 0 0 9 34 59 0 9 0 0 17 % I
% Lys: 17 67 0 0 0 0 0 0 0 17 59 9 9 17 9 % K
% Leu: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 25 9 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 25 67 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 9 0 0 0 0 0 17 9 0 % Q
% Arg: 59 0 0 0 0 17 59 0 0 0 9 9 0 17 59 % R
% Ser: 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 17 9 50 9 9 0 59 0 17 % T
% Val: 0 0 0 0 0 0 0 9 9 9 0 0 17 59 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _